Open AccessAccumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues
Author(s) -
Jared L. Zitnay,
Gang Seob Jung,
Allen H. Lin,
Zhao Qin,
Yang Li,
S. Michael Yu,
Markus J. Buehler,
Jeffrey A. Weiss
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aba2795
Subject(s) - mechanism (biology) , failure mechanism , cyclic stress , biophysics , chemistry , materials science , biology , composite material , physics , quantum mechanics
Denatured collagen accumulates during cyclic fatigue loading and explains the micro-damage hypothesis of overuse tissue injury.
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