Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span | Zendy

Ke Zou | Zendy; Silvi Rouskin | Zendy; Kevin Dervishi | Zendy; Mark A. McCormick | Zendy; Arjun N. Sasikumar | Zendy; Changhui Deng | Zendy; Zhibing Chen | Zendy; Matt Kaeberlein | Zendy; Rachel B. Brem | Zendy; Michael Polymenis | Zendy; Brian K. Kennedy | Zendy; Jonathan S. Weissman | Zendy; Jiashun Zheng | Zendy; Qi Ouyang | Zendy; Hao Li | Zendy

Open Access

Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span

Author(s) -

Ke Zou,

Silvi Rouskin,

Kevin Dervishi,

Mark A. McCormick,

Arjun N. Sasikumar,

Changhui Deng,

Zhibing Chen,

Matt Kaeberlein,

Rachel B. Brem,

Michael Polymenis,

Brian K. Kennedy,

Jonathan S. Weissman,

Jiashun Zheng,

Qi Ouyang,

Hao Li

Publication year - 2020

Publication title -

science advances

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.928

H-Index - 146

ISSN - 2375-2548

DOI - 10.1126/sciadv.aba1306

Subject(s) - methionine , biology , intracellular , methionine synthase , microbiology and biotechnology , regulator , biochemistry , gene , amino acid

Yeast cells lower their intracellular methionine level in response to glucose restriction to regulate metabolism and life span.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research