Interplay of m 6 A and H3K27 trimethylation restrains inflammation during bacterial infection
Author(s) -
Chenglei Wu,
Weixin Chen,
Jincan He,
Shouheng Jin,
Yukun Liu,
Yi Yang,
Zhuoxing Gao,
Jiayan Yang,
Jianhua Yang,
Jun Cui,
Wei Zhao
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aba0647
Subject(s) - demethylase , proinflammatory cytokine , histone , biology , messenger rna , microbiology and biotechnology , histone h3 , transcription (linguistics) , methyltransferase , gene silencing , transcription factor , demethylation , methylation , inflammation , gene expression , genetics , immunology , dna methylation , gene , linguistics , philosophy
m6 A controls the inflammatory response through cross-talk with H3K27me3, indicating the importance of m6 A in immune homeostasis.
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