Open AccessIntegrator restrains paraspeckles assembly by promoting isoform switching of the lncRNA NEAT1
Author(s) -
Jasmine Barra,
Gabriel Gaidosh,
Ezra Blumenthal,
Felipe Beckedorff,
Mina M. Tayari,
Nina Kirstein,
Tobias K. Karakach,
Torben Heick Jensen,
Francis Impens,
Kris Gevaert,
Eleonora Leucci,
Ramin Shiekhattar,
JeanChristophe Marine
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aaz9072
Subject(s) - gene isoform , biogenesis , polyadenylation , rna , microbiology and biotechnology , integrator , biology , chemistry , computational biology , computer science , genetics , gene , computer network , bandwidth (computing)
Integrator is a key regulator ofNEAT1 isoform switching and, thereby, paraspeckles biogenesis and chemosensitivity.
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