Open AccessIncreased vaccine tolerability and protection via NF-κB modulation
Author(s) -
Brittany A. Moser,
Rachel C. Steinhardt,
Yoseline Escalante-Buendia,
David A. Boltz,
KB Barker,
Brittney Cassaidy,
Matthew G. Rosenberger,
Stan Yoo,
Bethany McGonnigal,
Aaron P. EsserKahn
Publication year - 2020
Publication title -
science advances
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aaz8700
Subject(s) - tolerability , nf κb , modulation (music) , medicine , pharmacology , immunology , adverse effect , inflammation , physics , acoustics
Inflammation can be decoupled from the antigen-presenting actions of adjuvants using an immune potentiator that modulates NF-κB.
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