Open AccessGasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation
Author(s) -
Chunmei Ma,
Dongxue Yang,
Bingwei Wang,
Chunyan Wu,
Yuqing Wu,
Sheng Li,
Xue Liu,
Kara G. Lassen,
Lue Dai,
Shuo Yang
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aaz6717
Subject(s) - colitis , pyroptosis , inflammation , regulator , immunology , chemistry , microbiology and biotechnology , medicine , biology , biochemistry , inflammasome , gene
Gasdermin D in colonic macrophages controls cGAS-mediated inflammation, thereby protecting against the development of colitis.
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