Open AccessForce production of human cytoplasmic dynein is limited by its processivity
Author(s) -
Sibylle Brenner,
Florian Berger,
Lu Rao,
Matthew P. Nicholas,
Arne Gennerich
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aaz4295
Subject(s) - processivity , cytoplasm , dynein , production (economics) , motor protein , biophysics , physics , microbiology and biotechnology , chemistry , biology , microtubule , biochemistry , gene , dna replication , macroeconomics , economics
We present a novel experimental framework allowing for determination of the maximal force generation of weakly processive motors.
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