Open AccessNitric oxide disrupts bacterial cytokinesis by poisoning purine metabolism
Author(s) -
Jessica JonesCarson,
Atsushi Yahashiri,
Ju-Sim Kim,
Lin Liu,
Liam F. Fitzsimmons,
David S. Weiss,
Andrés VázquezTorres
Publication year - 2020
Publication title -
science advances
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aaz0260
Subject(s) - cytokinesis , purine , nitric oxide , purine metabolism , metabolism , chemistry , biochemistry , microbiology and biotechnology , biology , cell , cell division , enzyme , organic chemistry
An inflammatory mediator interrupts early steps in bacterial cell division by inhibiting nucleoside triphosphate synthesis.
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