Engineering light-controllable CAR T cells for cancer immunotherapy
Author(s) -
Ziliang Huang,
Yiqian Wu,
Molly E. Allen,
Yijia Pan,
Phillip Kyriakakis,
Shaoying Lu,
YaJu Chang,
Xin Wang,
Shu Chien,
Yingxiao Wang
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aay9209
Subject(s) - cancer immunotherapy , immunotherapy , cancer , cancer research , cancer cell , biology , immune system , computer science , immunology , genetics
Light-sensitive regulators were engineered to control genetic induction of CAR expression in T cells for cancer immunotherapy.
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