A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires
Author(s) -
Hidetaka Tanno,
Jonathan R. McDaniel,
Christopher Stevens,
William N. Voss,
Jie Li,
R. Durrett,
Jiwon Lee,
Jimmy Gollihar,
Yuri Tanno,
George Delidakis,
Arti Pothukuchy,
Jared W. Ellefson,
Jörg J. Goronzy,
Jennifer A. Maynard,
Andrew D. Ellington,
Gregory C. Ippolito,
George Georgiou
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aay9093
Subject(s) - t cell receptor , repertoire , throughput , dna sequencing , fragment (logic) , computational biology , computer science , biology , genetics , dna , t cell , algorithm , telecommunications , physics , immune system , wireless , acoustics
We report a simple and low-cost one-step high-throughput technology for sequencing the paired antibody/TCR repertoire.
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