Open AccessA new algorithm to convert a normal antibody into the corresponding catalytic antibody
Author(s) -
Emi Hifumi,
Hiroaki Taguchi,
Haruna Tsuda,
Tetsuro Minagawa,
Tamami aka,
Taizo Uda
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aay6441
Subject(s) - immunoglobulin light chain , catalysis , antibody , monoclonal antibody , chemistry , residue (chemistry) , mutant , peptide , substrate (aquarium) , epitope , biochemistry , combinatorial chemistry , biology , genetics , gene , ecology
We report a system for converting a monoclonal antibody to the corresponding catalytic antibody by deletion of Pro95 .
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