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Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion
Author(s) -
Jason R. Plemel,
Jo Anne Stratton,
Nathan J. Michaels,
Khalil S. Rawji,
Eric Zhang,
Sarthak Sinha,
Charbel S. Baaklini,
Yifei Dong,
Madelene F. S. Ho,
Kevin Thorburn,
Timothy N. Friedman,
Sana Jawad,
Claudia Silva,
Andrew V. Caprariello,
Vahid Hoghooghi,
Julie Yue,
Arzina Jaffer,
Kelly Lee,
Bradley J. Kerr,
Raj Midha,
Peter K. Stys,
Jeff Biernaskie,
V. Wee Yong
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aay6324
Subject(s) - microglia , macrophage , lesion , immune system , inflammation , central nervous system , neuroscience , biology , medicine , immunology , pathology , in vitro , biochemistry
Microglia respond to white matter injury with different populations that prevent macrophage dispersion into spared tissue.

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