Recruitment of CD103 + dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy | Zendy

JohnMichael Williford | Zendy; Jun Ishihara | Zendy; Ako Ishihara | Zendy; Aslan Mansurov | Zendy; Peyman Hosseinchi | Zendy; Tiffany M. Marchell | Zendy; Lambert Potin | Zendy; Melody A. Swartz | Zendy; Jeffrey A. Hubbell | Zendy

Open Access

Recruitment of CD103 ⁺ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy

Author(s) -

JohnMichael Williford,

Jun Ishihara,

Ako Ishihara,

Aslan Mansurov,

Peyman Hosseinchi,

Tiffany M. Marchell,

Lambert Potin,

Melody A. Swartz,

Jeffrey A. Hubbell

Publication year - 2019

Publication title -

science advances

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.928

H-Index - 146

ISSN - 2375-2548

DOI - 10.1126/sciadv.aay1357

Subject(s) - immunotherapy , chemokine , tumor microenvironment , immune system , cancer research , immunology , population , medicine , ccl5 , dendritic cell , cancer immunotherapy , cd8 , ccl4 , t cell , chemistry , il 2 receptor , carbon tetrachloride , environmental health , organic chemistry

Targeted delivery of CCL4 to the tumor stroma recruits CD103+ dendritic cells and enhances the efficacy of CPI immunotherapy.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research