Open AccessSCAN1-TDP1 trapping on mitochondrial DNA promotes mitochondrial dysfunction and mitophagy
Author(s) -
Arijit Ghosh,
Sangheeta Bhattacharjee,
Srijita Paul Chowdhuri,
Abhik Mallick,
Ishita Rehman,
Sudipta Basu,
Benu Brata Das
Publication year - 2019
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aax9778
Subject(s) - mitophagy , mitochondrial dna , microbiology and biotechnology , mitochondrion , trapping , genetics , biology , chemistry , autophagy , apoptosis , gene , ecology
Mitochondrial dysfunction promotes the etiology of neurodegenerative syndrome SCAN1.
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