Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis | Zendy

Alessandro Rimessi | Zendy; Chiara Pozzato | Zendy; Lorenzo Carparelli | Zendy; Alice S. Rossi | Zendy; Serena Ranucci | Zendy; Ida De Fino | Zendy; Cristina Cigana | Zendy; Anna Maria Talarico | Zendy; Mariusz R. Wiȩckowski | Zendy; Carla M. P. Ribeiro | Zendy; Claudio Trapella | Zendy; Giacomo Rossi | Zendy; Giulio Cabrini | Zendy; Alessandra Bragonzi | Zendy; Paolo Pinton | Zendy

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Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis

Author(s) -

Alessandro Rimessi,

Chiara Pozzato,

Lorenzo Carparelli,

Alice S. Rossi,

Serena Ranucci,

Ida De Fino,

Cristina Cigana,

Anna Maria Talarico,

Mariusz R. Wiȩckowski,

Carla M. P. Ribeiro,

Claudio Trapella,

Giacomo Rossi,

Giulio Cabrini,

Alessandra Bragonzi,

Paolo Pinton

Publication year - 2020

Publication title -

science advances

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.928

H-Index - 146

ISSN - 2375-2548

DOI - 10.1126/sciadv.aax9093

Subject(s) - cystic fibrosis , inflammation , lung , medicine , uniporter , calcium , fibrosis , mitochondrion , pathology , immunology , biology , microbiology and biotechnology , biochemistry , cytosol , enzyme

Mitochondrial therapy offers an alternative strategy for attenuation of hyperinflammation in cystic fibrosis lung disease.

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