Open AccessCryo–electron microscopy structure and analysis of the P-Rex1–Gβγ signaling scaffold
Author(s) -
Jennifer N. Cash,
Sarah Urata,
Sheng Li,
Sandeep K. Ravala,
Larisa Avramova,
Michael Shost,
J. Silvio Gutkind,
J.J.G. Tesmer,
Michael A. Cianfrocco
Publication year - 2019
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aax8855
Subject(s) - electron microscope , scaffold , scaffold protein , microbiology and biotechnology , cryo electron microscopy , chemistry , nanotechnology , biophysics , signal transduction , materials science , biology , biomedical engineering , physics , engineering , optics
The cryo-EM structure of P-Rex1 bound to Gβγ reveals the configuration of an important membrane-associated signaling scaffold.
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