Structural insights into the EGO-TC–mediated membrane tethering of the TORC1-regulatory Rag GTPases
Author(s) -
Tianlong Zhang,
Marie-Pierre Péli-Gulli,
Zhen Zhang,
Xin Tang,
Jie Ye,
Claudio De Virgilio,
Jianping Ding
Publication year - 2019
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aax8164
Subject(s) - gtpase , tethering , microbiology and biotechnology , chemistry , membrane , biology , biochemistry
The crystal structure of the EGO complex elucidates the membrane recruitment of the TORC1-regulatory Gtr1-Gtr2 Rag GTPases.
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