Controlled ploidy reduction of pluripotent 4n cells generates 2n cells during mouse embryo development
Author(s) -
João Frade,
Shoma Nakagawa,
Paola Cortes,
Umberto Di Vicino,
Neus Romo,
Frederic Lluı́s,
Maria Pia Cosma
Publication year - 2019
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aax4199
Subject(s) - embryo , ploidy , induced pluripotent stem cell , microbiology and biotechnology , biology , reduction (mathematics) , embryogenesis , embryonic stem cell , chemistry , genetics , gene , geometry , mathematics
Mouse pluripotent tetraploid cells generate diploid cells during embryogenesis through nonrandom chromosome segregation.
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