Open AccessVancomycin relieves mycophenolate mofetil–induced gastrointestinal toxicity by eliminating gut bacterial β-glucuronidase activity
Author(s) -
Michael R. Taylor,
Kyle L. Flannigan,
Hannah Rahim,
Amina Mohamud,
Ian A. Lewis,
Simon A. Hirota,
Steven C. Greenway
Publication year - 2019
Publication title -
science advances
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aax2358
Subject(s) - mycophenolate , toxicity , vancomycin , medicine , pharmacology , microbiology and biotechnology , biology , bacteria , transplantation , staphylococcus aureus , genetics
Toxicity from the immunosuppressant mycophenolate mofetil is prevented by eliminating gut bacteria expressing β-glucuronidase.
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