Open AccessHierarchical assembly governs TRIM5α recognition of HIV-1 and retroviral capsids
Author(s) -
Katarzyna Skorupka,
Marcin Roganowicz,
Devin E. Christensen,
Yueping Wan,
Owen Pornillos,
Barbie K. GanserPornillos
Publication year - 2019
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aaw3631
Subject(s) - capsid , human immunodeficiency virus (hiv) , virology , computational biology , retrovirus , biology , virus
TRIM5α combines distinct modes of binding into successively higher-order structures to recognize HIV-1 and retroviral capsids.
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