Open AccessSoft extracellular matrix enhances inflammatory activation of mesenchymal stromal cells to induce monocyte production and trafficking
Author(s) -
Sing Wan Wong,
Stephen Lenzini,
Madeline H. Cooper,
David Mooney,
JaeWon Shin
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aaw0158
Subject(s) - extracellular matrix , mesenchymal stem cell , paracrine signalling , microbiology and biotechnology , monocyte , stromal cell , matrix (chemical analysis) , extracellular , chemistry , biology , immunology , biochemistry , cancer research , receptor , chromatography
Soft extracellular matrix boosts the activation of MSCs by TNFα to generate and recruit monocytes in a paracrine manner.
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