Transient activation of the UPR ER is an essential step in the acquisition of pluripotency during reprogramming
Author(s) -
Milos Simic,
Erica A. Moehle,
Robert T. Schinzel,
Franziska K. Lorbeer,
Jonathan J. Halloran,
Kartoosh Heydari,
Melissa Sanchez,
Damien Jullié,
Dirk Hockemeyer,
Andrew Dillin
Publication year - 2019
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aaw0025
Subject(s) - reprogramming , microbiology and biotechnology , transient (computer programming) , chemistry , biology , computer science , cell , biochemistry , operating system
A transient activation of the unfolded protein response of the ER is a key factor of cellular reprogramming success.
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