Hybrid nanocarriers incorporating mechanistically distinct drugs for lymphatic CD4 + T cell activation and HIV-1 latency reversal
Author(s) -
Shijie Cao,
Sarah D. Slack,
Claire Levy,
Sean M. Hughes,
Yonghou Jiang,
Christopher Yogodzinski,
Pavitra Roychoudhury,
Keith R. Jerome,
Joshua T. Schiffer,
Florian Hladik,
Kim A. Woodrow
Publication year - 2019
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aav6322
Subject(s) - nanocarriers , latency (audio) , lymph , reversing , human immunodeficiency virus (hiv) , lymphatic system , cancer research , lentivirus , chemistry , immunology , microbiology and biotechnology , medicine , pharmacology , biology , drug , materials science , computer science , pathology , telecommunications , viral disease , composite material
Targeted nanocarriers deliver HIV-1 latency-reversing agents to CD4+ T cells in the lymph nodes.
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