Open AccessCryo-EM structure of phosphodiesterase 6 reveals insights into the allosteric regulation of type I phosphodiesterases
Author(s) -
Sahil Gulati,
Krzysztof Palczewski,
Andreas Engel,
Henning Stahlberg,
Ľubomír Kováčik
Publication year - 2019
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aav4322
Subject(s) - allosteric regulation , phosphodiesterase , linker , biophysics , protein structure , visual phototransduction , molecular machine , adenylate kinase , cyclic nucleotide phosphodiesterase , chemistry , biology , microbiology and biotechnology , biochemistry , receptor , enzyme , genetics , computer science , retinal , operating system
We report the cryo-EM structure of rod photoreceptor phosphodiesterase 6.
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