A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity
Author(s) -
Evan M. Cornett,
Bradley M. Dickson,
Krzysztof Krajewski,
Nicholas Spellmon,
Andrew Umstead,
Robert M. Vaughan,
Kevin M. Shaw,
Philip Versluis,
Martis W. Cowles,
J.S. Brunzelle,
Zhe Yang,
Irving E. Vega,
Zu-Wen Sun,
Scott B. Rothbart
Publication year - 2018
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aav2623
Subject(s) - lysine , methyltransferase , proteomics , substrate (aquarium) , proteome , selectivity , computational biology , substrate specificity , biochemistry , chemistry , methylation , biology , enzyme , gene , amino acid , ecology , catalysis
Mapping lysine methyltransferase substrate selectivity reveals gaps in the proteome-wide curation of lysine methylomes.
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