Open AccessThe combined importance of finite dimensions, anisotropy, and pre-stress in acoustoelastography
Author(s) -
Joseph Crutison,
Michael Sun,
Thomas J. Royston
Publication year - 2022
Publication title -
the journal of the acoustical society of america/the journal of the acoustical society of america
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.619
H-Index - 187
eISSN - 1520-8524
pISSN - 0001-4966
DOI - 10.1121/10.0010110
Subject(s) - elastography , magnetic resonance elastography , viscoelasticity , isotropy , anisotropy , materials science , waveguide , intravascular ultrasound , ultrasound , boundary value problem , acoustics , material properties , biomedical engineering , physics , optics , composite material , radiology , medicine , quantum mechanics , optoelectronics
Dynamic elastography, whether based on magnetic resonance, ultrasound, or optical modalities, attempts to reconstruct quantitative maps of the viscoelastic properties of biological tissue, properties that are altered by disease and injury, by noninvasively measuring mechanical wave motion in the tissue. Most reconstruction strategies that have been developed neglect boundary conditions, including quasistatic tensile or compressive loading resulting in a nonzero prestress. Significant prestress is inherent to the functional role of some biological tissues currently being studied using elastography, such as skeletal and cardiac muscle, arterial walls, and the cornea. In the present article, we review how prestress alters both bulk mechanical wave motion and wave motion in one- and two-dimensional waveguides. Key findings are linked to studies on skeletal muscle and the human cornea, as one- and two-dimensional waveguide examples. This study highlights the underappreciated combined acoustoelastic and waveguide challenge to elastography. Can elastography truly determine viscoelastic properties of a material when what it is measuring is affected by both these material properties and unknown prestress and other boundary conditions?