Open AccessExperience in implementing continuous arterial spin labeling on a commercial MR scanner
Author(s) -
Steger Theodore R.,
Jackson Edward F.
Publication year - 2005
Publication title -
journal of applied clinical medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.83
H-Index - 48
ISSN - 1526-9914
DOI - 10.1120/jacmp.v6i1.2068
Subject(s) - scanner , spin offs , arterial spin labeling , nuclear medicine , medical physics , nuclear magnetic resonance , computer science , medicine , physics , radiology , business , artificial intelligence , magnetic resonance imaging , industrial organization
Continuous arterial spin labeling (CASL) is a technique for performing quantitative perfusion measurements without the need for exogenous contrast agent administration. This technique has seen limited use in the clinic due to problems of poor sensitivity and the potential for artifacts. In addition, CASL requires the application of long‐duration radiofrequency pulses and the acquisition of a large number of images, which can cause difficulties when implemented on commercial MR scanners. This work details our experience in implementing CASL on a commercial MR scanner for the measurement of cerebral blood flow, including pitfalls regarding hardware, radiofrequency energy deposition, and practical application in human subjects. Results of studies to determine the optimal acquisition procedures are also presented. PACS number: 87.61.‐c