Open AccessCommissioning and initial experience with the first clinical gantry‐mounted proton therapy system
Author(s) -
Zhao Tianyu,
Sun Baozhou,
Grantham Kevin,
Rankine Leith,
Cai Bin,
Goddu Sreekrishna M.,
Santanam Lakshmi,
Knutson Nels,
Zhang Tiezhi,
Reilly Michael,
Bottani Beth,
Bradley Jeffrey,
Mutic Sasa,
Klein Eric E.
Publication year - 2016
Publication title -
journal of applied clinical medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.83
H-Index - 48
ISSN - 1526-9914
DOI - 10.1120/jacmp.v17i2.5868
Subject(s) - proton therapy , medical physics , radiation treatment planning , credentialing , nuclear medicine , medicine , project commissioning , delivery system , radiation therapy , radiology , biomedical engineering , publishing , political science , law , medical education
The purpose of this study is to describe the comprehensive commissioning process and initial clinical experience of the Mevion S250 proton therapy system, a gantry‐mounted, single‐room proton therapy platform clinically implemented in the S. Lee Kling Proton Therapy Center at Barnes‐Jewish Hospital in St. Louis, MO, USA. The Mevion S250 system integrates a compact synchrocyclotron with a C‐inner gantry, an image guidance system and a 6D robotic couch into a beam delivery platform. We present our commissioning process and initial clinical experience, including i) CT calibration; ii) beam data acquisition and machine characteristics; iii) dosimetric commissioning of the treatment planning system; iv) validation through the Imaging and Radiation Oncology Core credentialing process, including irradiations on the spine, prostate, brain, and lung phantoms; v) evaluation of localization accuracy of the image guidance system; and vi) initial clinical experience. Clinically, the system operates well and has provided an excellent platform for the treatment of diseases with protons. PACS number(s): 87.55.ne, 87.56.bd