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Magnetic resonance imaging of thermal coagulation effects in a phantom for calibrating thermal therapy devices
Author(s) -
Bouchard LouisSerge,
Bronskill Michael J.
Publication year - 2000
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.598980
Subject(s) - imaging phantom , materials science , thermal , magnetic resonance imaging , ultrasound , biomedical engineering , microwave , resonance (particle physics) , nuclear magnetic resonance , radiology , medicine , computer science , thermodynamics , physics , telecommunications , particle physics
A material has been developed and tested that permanently records thermal response patterns from heating devices. The material consists of a mixture of polyacrylamide and 18% w/w bovine serum albumin. Thermal denaturation is complete when the local temperature exceeds 70 ° C , causing a large reduction in the T 2of the material. Three‐dimensional distributions of “thermal damage” can be assessed using standard magnetic resonance imaging sequences. The material works well with microwave heating devices and is adaptable for use with ultrasound, radio‐frequency, or laser heating devices. Suggested uses include characterizing heating devices prior to treatment and developing new clinical applications for thermal therapies.