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Refraction‐enhanced x‐ray imaging of mouse lung using synchrotron radiation source
Author(s) -
Yagi N.,
Suzuki Y.,
Umetani K.,
Kohmura Y.,
Yamasaki K.
Publication year - 1999
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.598735
Subject(s) - refraction , synchrotron radiation , optics , physics , radiation , x ray optics , absorption (acoustics) , medical imaging , high energy x rays , spring 8 , x ray , beam (structure) , medicine , radiology , beamline
The low divergent x‐ray beam from the third‐generation synchrotron radiation source such as SPring‐8 enables us to observe refraction of x rays that is in the range of microradians. Under an experimental condition for which ray optics is a good approximation, we found that the refraction produces a high‐contrast projection image of a mouse when it was recorded at 6.5 m behind the specimen. Especially, the lung is visualized far better than with the conventional imaging which utilizes absorption of x rays. This is a promising new technique for the diagnosis of diseases in the human lung with a low radiation dose.