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Spatial resolution of imaging with diffusing light: Edge spread function measurements on a realistic tissue phantom
Author(s) -
Cubeddu Rinaldo,
Pifferi Antonio,
Taroni Paola,
Torricelli Alessandro,
Valentini Gianluca
Publication year - 1999
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.598545
Subject(s) - imaging phantom , transmittance , optics , scattering , image resolution , attenuation coefficient , intensity (physics) , absorption (acoustics) , materials science , resolution (logic) , optical transfer function , physics , computer science , artificial intelligence
A realistic tissue phantom was used to study the spatial resolution of time‐resolved transmittance imaging techniques based on time gating and on the plot of the optical coefficients obtained from the fit to a theoretical model. Time‐resolved transmittance curves were collected along a line across a sharp transition between two regions of different, but realistic, optical properties. The effect of scattering and absorption edges were examined to get a deeper insight into the problem of imaging both scattering and absorption inhomogeneities. For both the fitted optical parameters and the integrated intensity, the edge spread function was evaluated and fitted to an error function, providing quantitative information on both spatial resolution and edge location. The plot of the fitted scattering coefficient and the intensity integrated within an early gate have similar resolution, while the performance of the fitted absorption coefficient is definitely worse. The edge location is more sensitive to the optical contrast with the fitted scattering than with the integrated intensity.