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An active set algorithm for treatment planning optimization
Author(s) -
Hristov D. H.,
Fallone B. G.
Publication year - 1997
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.598034
Subject(s) - radiation treatment planning , algorithm , set (abstract data type) , computer science , mathematical optimization , medical physics , mathematics , medicine , radiation therapy , radiology , programming language
An active set algorithm for optimization of radiation therapy dose planning by intensity modulated beams has been developed. The algorithm employs a conjugate‐gradient routine for subspace minimization in order to achieve a higher rate of convergence than the widely used constrained steepest‐descent method at the expense of a negligible amount of overhead calculations. The performance of the new algorithm has been compared to that of the constrained steepest‐descent method for various treatment geometries and two different objectives. The active set algorithm is found to be superior to the constrained steepest descent, both in terms of its convergence properties and the residual value of the cost functions at termination. Its use can significantly accelerate the design of conformal plans with intensity modulated beams by decreasing the number of time‐consuming dose calculations.