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Computer simulation of time‐gated transillumination and reflection of biological tissues and tissuelike phantoms
Author(s) -
Michielsen K.,
De Raedt H.,
Garcı́a N.
Publication year - 1997
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.597955
Subject(s) - transillumination , reflection (computer programming) , optics , millimeter , imaging phantom , medical imaging , mammography , computer science , breast cancer , physics , artificial intelligence , cancer , medicine , programming language
A simulation technique is employed to explore the possibility of locating millimeter‐sized objects, immersed in turbid media, from time‐gated measurements of the transmitted or reflected light. The simulation results for tissuelike phantoms are compared to experimental transillumination data and excellent agreement is found. Simulations of time‐gated reflection experiments show that it is possible to detect objects of 1 mm diameter. This may open new possibilities for medical diagnosis of breast cancer in an early stage.