Premium
Phase‐contrast radiographs of nonstained rat cerebellar specimen
Author(s) -
Momose Atsushi,
Fukuda Jun
Publication year - 1995
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.597472
Subject(s) - radiography , medical imaging , phase contrast microscopy , contrast (vision) , phase (matter) , medicine , nuclear medicine , phase contrast imaging , radiology , optics , physics , quantum mechanics
Phase‐contrast radiography using an x‐ray interferometer is presented for observing organic matter. High sensitivity of phase‐contrast radiography is demonstrated with a rat cerebellar specimen without staining it with a contrast medium. The layer structure of the cerebellum can be observed in the obtained image while there is no clear structure in the corresponding absorption‐contrast image. Quantitative image analysis is made possible by converting an x‐ray interference pattern to an x‐ray phase shift distribution. The lipid distribution in the cerebellum is discussed by evaluating x‐ray phase shifts before and after lipid removal.