Premium
Thick beryllium target as an epithermal neutron source for neutron capture therapy
Author(s) -
Wang C.K. Chris,
Moore Brian R.
Publication year - 1994
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.597269
Subject(s) - neutron , beryllium , neutron capture , neutron source , neutron temperature , proton , beam (structure) , nuclear physics , neutron radiation , materials science , radiochemistry , physics , chemistry , optics
Accelerator‐based intense epithermal neutron sources for Neutron Capture Therapy (NCT) have been considered as an alternative to nuclear reactors. Lithium (Li) has generally received the widest attention for this application, since the threshold energy is low and neutron yield is high. Because of the poor thermal and chemical properties of Li and the need for heat removal in the target, the design of Li targets has been quite difficult. Beryllium (Be) has been thought of as an alternative target because of its good thermal and chemical properties and reasonable neutron yield. However, in order to have a neutron yield comparable to that of a thick Li target bombarded with 2.5 MeV protons, the proton energy required for a thick Be target must be approaching 4 MeV. Consequently, the neutrons emitted are more energetic. In addition, a significant amount of high‐energy gamma rays, which is undesirable, will occur when Be is bombarded with low‐energy protons. Regardless of the more energetic neutrons and additional gamma rays, in this paper it is shown that it is possible to develop a high‐quality and high‐intensity epithermal neutron beam based on a thick Be target for NCT treatment. For a fixed proton current, the optimal Be‐target‐based beam (with 4‐MeV protons) can produce a neutron beam, with both quality and intensity slightly better than those produced by the optimal Li‐target‐based beam (with 2.5‐MeV protons). The single‐session NCT treatment time for the optimal Be‐target‐based beam is estimated to be 88 min for a proton current of 50 mA. The major advantage of a Be target over a Li target is the simplicity in design, construction, operation, and maintenance.