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Selection of fat‐equivalent materials in postprocessing dual‐energy quantitative CT
Author(s) -
Steenbeek Jack C. M.,
van Kuijk Cornelis,
Grashuis Jan L.,
van Panthaleon van Eck Reinier B.
Publication year - 1992
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.596823
Subject(s) - dual energy , characterization (materials science) , calibration , materials science , biomedical engineering , mathematics , bone mineral , osteoporosis , medicine , statistics , pathology , nanotechnology
Postprocessing dual‐energy QCT is supposed to be able to predict the bone mineral more accurately than single‐energy QCT. In addition, the fat content in the vertebral body can be determined. To this aim, some methods include fat‐equivalent materials in the calibration device. However, the choice of an appropriate fat‐equivalent material is difficult. To solve this selection problem, a method has been developed in which the x‐ray interactions of tissue are characterized by three energy‐independent parameters. For five different known constituents of anatomical fat, fat‐equivalent materials are evaluated. It is shown that it is not possible to find one fat‐equivalent material for all anatomical fat compositions. For this reason, the influence of a mismatch between the characterization parameters of anatomical fat compositions and fat‐equivalent materials has been evaluated. It is shown that a mismatch in tissue characterization parameters can result in deviations of 10% in the bone mineral content and more than 300% in the estimated fat contents.