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Imaging of spatial radiation dose distribution in agarose gels using magnetic resonance
Author(s) -
Appleby A.,
Christman E. A.,
Leghrouz A.
Publication year - 1987
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.596052
Subject(s) - irradiation , radiation , materials science , absorbed dose , nuclear magnetic resonance , ionizing radiation , proton , dosimetry , resonance (particle physics) , radiochemistry , chemistry , optics , nuclear medicine , atomic physics , physics , nuclear physics , medicine
Radiation dose distributions are conventionally measured using ionization chambers or diodes in liquid phantoms, or in two dimensions using film. This work describes a new application of magnetic resonance imaging to radiation dose planning. Agarose gels containing ferrous sulfate, sulfuric acid, and benzoic acid have been irradiated with 1 3 7 Cs gamma rays and 6–14 MeV electrons, to doses of up to 20 Gy. The dose distributions have been imaged by magnetic resonance, making use of the effect on the T 1 proton relaxation times of the radiolytic Fe 3 + . The image intensity was proportional to doses of up to 10 Gy, and images were stable for at least 24 h postirradiation. The G value for Fe 3 + production was about 100 (molecules per 100 eV absorbed).