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Relaxation times of normal and atrophied muscle
Author(s) -
LeBlanc Adrian,
Evans Harlan,
Schonfeld Ernesto,
Ford Joseph,
Marsh Cherri,
Schneider Victor,
Johnson Philip
Publication year - 1986
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.595970
Subject(s) - atrophy , relaxation (psychology) , muscle atrophy , magnetic resonance imaging , nuclear magnetic resonance , blood flow , anatomy , medicine , materials science , pathology , physics , radiology
Magnetic resonance imaging is being used to investigate physiological changes induced by microgravity. Using human (bed rest) and animal (tail suspension) models simulating zero gravity, muscle atrophy was studied. Despite significant physiological changes in muscle mass, distribution of blood flow, and muscle water, no changes in muscle proton relaxation times were found at several different resonant frequencies (6, 10, 20, and 200 MHz). These results suggest that observed changes in relaxation times as reported in pathologic studies are likely due to the pathological changes and not the accompanying muscle atrophy.