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Effect of background correction on left ventricular ejection fraction calculation through analysis of a simple cardiac model
Author(s) -
Grove D. E.,
Stein R. A.,
Nosil J.
Publication year - 1986
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.595824
Subject(s) - ejection fraction , simple (philosophy) , cardiology , fraction (chemistry) , medicine , heart failure , chemistry , organic chemistry , philosophy , epistemology
The dependence of the left ventricular ejection fraction calculation on the background correction in gated cardiac blood pool studies is examined by analyzing a simple cardiac model. It is shown that the ejection fraction is relatively insensitive to the background correction when an accurately determined variable region of interest is used, but that with a fixed region of interest the background correction must be accurately estimated. A similar ejection fraction–background correction relationship is obtained in the analysis of clinical cardiac data. Based on the cardiac model, two methods are suggested which, with further investigation and refinement, may lead to a more accurate and consistent technique for determining ejection fraction and background.