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Measurements of the distribution of technetium‐99 m sulfur colloid and technetium‐99 m HEDP in normal humans
Author(s) -
Grossman Laurence W.,
Sodd Vincent J.,
Nishiyama Hiroshi,
Feller Paul A.,
Hoops Richard G.
Publication year - 1983
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.595379
Subject(s) - technetium , technetium 99m , technetium 99 , nuclear medicine , dosimetry , colloid , radiochemistry , radiation dose , chemistry , medicine , scintigraphy
Technetium‐99 m sulfur colloid and technetium‐99 m hydroxyethylidene diphosphonate (HEDP) are two radiopharmaceuticals that have been widely used in nuclear medicine. Radiation dose estimates for both materials have been published in the literature and are found in the package inserts of the commercial kits. However, these estimates were made without the benefit of quantitative human organ uptake data. Estimates of absorbed radiation dose to the kidneys differ by nearly a factor of 6 between the two calculations for HEDP. The results of this study are in agreement with the lower previous estimate. Other than that one exception, agreement of the previous estimates with the measurements reported here is surprisingly good.