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Temperature rise during photoradiation therapy of malignant tumors
Author(s) -
Svaasand Lars O.,
Doiron Daniel R.,
Dougherty Thomas J.
Publication year - 1983
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.595373
Subject(s) - optical fiber , materials science , absorption (acoustics) , optical power , scattering , optoelectronics , light scattering , thermal conductivity , optics , blood flow , biomedical engineering , medicine , physics , radiology , laser , composite material
This report discusses the optical and thermal distribution during photoradiation therapy of malignant tumors. Emphasis is put on the therapeutic procedure with the light dose delivered through an inserted optical fiber. Theoretical predictions and experimental results indicate that the temperature rise during the procedure may give rise to hyperthermal cell kill. The report discusses the extent of the regions with hyperthermal bioeffects in terms of tissue parameters as optical absorption and scattering, thermal conductivity, specific heat, blood flow, and optical dose parameters as optical power and exposure time.