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In vivo quantitation of lesion radioactivity using external counting methods
Author(s) -
Thomas Stephen R.,
Maxon Harry R.,
Kereiakes James G.
Publication year - 1976
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.594287
Subject(s) - nuclear medicine , in vivo , medical imaging , medical physics , physics , medicine , radiology , biology , microbiology and biotechnology
Quantitative external counting methods for the in vivo determination of the activity uniformly distributed in an area of interest (lesion) have been developed. The theoretical work has been extended to include the effects of regions of differing attenuation coefficient and of non‐target organ activity in the tissue surrounding the lesion. A clinical quantitative procedure utilizing a “calibrated” gamma camera and associated computer system is described. Studies including a bone substitute material in a water phantom confirmed the basic theoretical work.