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SU‐E‐J‐25: End‐To‐End (E2E) Testing On TomoHDA System Using a Real Pig Head for Intracranial Radiosurgery
Author(s) -
Corradini N,
Leick M,
Bonetti M,
Negretti L
Publication year - 2015
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.4924112
Subject(s) - repeatability , nuclear medicine , radiosurgery , cadaveric spasm , head and neck , rotation (mathematics) , head (geology) , medicine , mathematics , radiation therapy , anatomy , radiology , geometry , surgery , geology , statistics , geomorphology
Purpose: To determine the MVCT imaging uncertainty on the TomoHDA system for intracranial radiosurgery treatments. To determine the end‐to‐end (E2E) overall accuracy of the TomoHDA system for intracranial radiosurgery. Methods: A pig head was obtained from the butcher, cut coronally through the brain, and preserved in formaldehyde. The base of the head was fixed to a positioning plate allowing precise movement, i.e. translation and rotation, in all 6 axes. A repeatability test was performed on the pig head to determine uncertainty in the image bone registration algorithm. Furthermore, the test studied images with MVCT slice thicknesses of 1 and 3 mm in unison with differing scan lengths. A sensitivity test was performed to determine the registration algorithm's ability to find the absolute position of known translations/rotations of the pig head. The algorithm's ability to determine absolute position was compared against that of manual operators, i.e. a radiation therapist and radiation oncologist. Finally, E2E tests for intracranial radiosurgery were performed by measuring the delivered dose distributions within the pig head using Gafchromic films. Results: The repeatability test uncertainty was lowest for the MVCTs of 1‐mm slice thickness, which measured less than 0.10 mm and 0.12 deg for all axes. For the sensitivity tests, the bone registration algorithm performed better than human eyes and a maximum difference of 0.3 mm and 0.4 deg was observed for the axes. E2E test results in absolute position difference measured 0.03 ± 0.21 mm in x‐axis and 0.28 ± 0.18 mm in y‐axis. A maximum difference of 0.32 and 0.66 mm was observed in × and y, respectively. The average peak dose difference between measured and calculated dose was 2.7 cGy or 0.4%. Conclusion: Our tests using a pig head phantom estimate the TomoHDA system to have a submillimeter overall accuracy for intracranial radiosurgery.