Premium
Synchrotron radiation imaging is a powerful tool to image brain microvasculature
Author(s) -
Zhang Mengqi,
Peng Guanyun,
Sun Danni,
Xie Yuanyuan,
Xia Jian,
Long Hongyu,
Hu Kai,
Xiao Bo
Publication year - 2014
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.4865784
Subject(s) - microangiography , neuroimaging , neurovascular bundle , medical imaging , functional imaging , preclinical imaging , synchrotron radiation , medical physics , medicine , radiology , pathology , physics , in vivo , optics , microbiology and biotechnology , psychiatry , biology
Synchrotron radiation (SR) imaging is a powerful experimental tool for micrometer‐scale imaging of microcirculation in vivo . This review discusses recent methodological advances and findings from morphological investigations of cerebral vascular networks during several neurovascular pathologies. In particular, it describes recent developments in SR microangiography for real‐time assessment of the brain microvasculature under various pathological conditions in small animal models. It also covers studies that employed SR‐based phase‐contrast imaging to acquire 3D brain images and provide detailed maps of brain vasculature. In addition, a brief introduction of SR technology and current limitations of SR sources are described in this review. In the near future, SR imaging could transform into a common and informative imaging modality to resolve subtle details of cerebrovascular function.