Premium
An anatomically realistic and adaptable prostate phantom for laser thermotherapy treatment planning
Author(s) -
Betrouni N.,
Nevoux P.,
Leroux B.,
Colin P.,
Puech P.,
Mordon S.
Publication year - 2013
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.4788673
Subject(s) - imaging phantom , medical physics , radiation treatment planning , medical imaging , prostate , dosimetry , nuclear medicine , biomedical engineering , medicine , radiation therapy , radiology , cancer
Purpose: To construct a phantom for prostate cancer laser based thermotherapy treatment planning and simulation.Methods: A realistic and adaptable prostate phantom was designed. It exhibits the following properties: valid and complete description of the prostate anatomy, material with similar optical properties of prostate tissues and compatibility with clinical imaging protocols mainly multiparametric magnetic resonance (MR) and transrectal ultrasound imaging (TRUS).Results: Preliminary experiments with the phantom using an interstitial laser treatment protocol allowed obtaining results similar to those obtained on preclinical model.Conclusions: These results proved that this phantom could allow a real simulation of laser therapy procedure: target definition and fibers’ placement optimization using MR imaging, treatment delivery, and finally treatment monitoring using TRUS imaging.