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TU‐E‐BRB‐07: Optimal Treatment Beam Fluence Generation for Volumetric Arc Therapy Using Dose Image Backprojection with Initial Corona Calculation
Author(s) -
Barbiere J,
Hanley J
Publication year - 2010
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.3469290
Subject(s) - imaging phantom , iterative reconstruction , iterative method , medical imaging , algorithm , fluence , computer science , mathematics , nuclear medicine , physics , computer vision , optics , artificial intelligence , medicine , laser
Purpose: Derive a novel solution to the initial premise that IMRT fluence can be easily calculated using dose image backprojection. Method and Materials: Calculations were performed using MATLAB with the imaging toolbox using parallel beam geometry. A phantom matrix P was constructed with a concave target, simultaneous integrated boost, and organ at risk with respective desired percent doses of 100, 110, and 40. Let R:SP be the backprojection of sinogram S of P. Iterative reconstruction using standard Ratio Method converges on a solution by computing Si+1 = Si * (P / R:SiP). For the novel Corona Method, we compute the corona using iterative backprojection reconstruction using ratios on only the target volumes T, T’ = R:S0T, and then superimpose the organ at risk, P’ = T’ + OAR. Iterative backprojection on P’ is then performed by successive addition correction, Si+1 = Si‐1 + (SO − Si), where SO is the sinogram of P’. Any negative intensities are set to zero during the iteration process. Target coverage is improved using the Compensated Phantom Method by computing a revised target based on the results Z of the process described thus far. We then define a new target T” = T’/Z and superimpose the OAR, such that P” = T” + OAR. The final procedure is to perform additive iteration constrained to contain only positive intensities. Results: Ratio Method: Target and boost areas receive their respective dose goals but the organ at risk unacceptable. Corona Method : OAR acceptable but poor target coverage. Compensated Phantom Method : Acceptable target coverage and the OAR goal is achieved. Conclusion: Dose image backprojection with initial corona calculation significantly reduces the dose to the organ at risk while maintaining acceptable target coverage.