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Locating and targeting moving tumors with radiation beams
Author(s) -
Dieterich Sonja,
Cleary Kevin,
D’Souza Warren,
Murphy Martin,
Wong Kenneth H.,
Keall Paul
Publication year - 2008
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.3020593
Subject(s) - quality assurance , computer science , medical physics , implementation , translation (biology) , radiation therapy , medicine , radiology , pathology , biology , software engineering , biochemistry , external quality assessment , messenger rna , gene
The current climate of rapid technological evolution is reflected in newer and better methods to modulate and direct radiation beams for cancer therapy. This Vision 20 ∕ 20 paper focuses on part of this evolution, locating and targeting moving tumors. The two processes are somewhat independent and in principle different implementations of the locating and targeting processes can be interchanged. Advanced localization and targeting methods have an impact on treatment planning and also present new challenges for quality assurance (QA), that of verifying real‐time delivery. Some methods to locate and target moving tumors with radiation beams are currently FDA approved for clinical use—and this availability and implementation will increase with time. Extensions of current capabilities will be the integration of higher order dimensionality, such as rotation and deformation in addition to translation, into the estimate of the patient pose and real‐time reoptimization and adaption of delivery to the dynamically changing anatomy of cancer patients.