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Poster — Thurs Eve‐17: Stand alone software for deforming delivered dose distributions to account for daily anatomical variations in prostate patients treated on the TomoTherapy Hi‐Art II system
Author(s) -
Rivest R,
Riauka T,
Murtha A,
Fallone G
Publication year - 2008
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.2965936
Subject(s) - tomotherapy , radiation treatment planning , voxel , medical physics , dosimetry , nuclear medicine , computer science , software , medicine , medical imaging , image registration , radiation therapy , radiology , computer vision , image (mathematics) , programming language
The acquisition of daily megavoltage (MV)‐CT images provides an invaluable tool in the delivery of adaptive radiotherapy (ART) on the TomoTherapy Hi‐ART II system. Using TomoTherapy's Planned Adaptive software, delivery sinograms can be applied to pre‐treatment MVCT images to generate daily delivered dose distributions, allowing for the potential comparison of planned and delivered doses. However, daily patient anatomical variations complicate the task and accurate comparison requires that daily doses be evaluated in the same references frame as the planned dose. Each anatomical point in daily MVCT images must be mapped to its corresponding point in the patient planning CT and that deformation map must be applied to the daily dose distribution. Stand alone software has been developed for the comparison of planned and delivered doses for TomoTherapy prostate patients. Software inputs are the planning CT, planning structure data, planned dose distribution, daily MVCT and delivered dose distribution. The software uses an in‐house developed automatic voxel‐based deformable registration algorithm designed and optimized specifically for the registration of prostate CT images to achieve anatomical correspondence between MVCT and planning images. The resultant deformation map is applied to the daily dose distribution and the software outputs the deformed daily dose distribution in the planning CT's reference frame, as well as a delivered DVH for each of the planning CT's ROI. The software allows for a number of potential research opportunities, in particular, the calculation of the cumulative dose delivered over the course of treatment for prostate patients treated on the Hi‐Art II system.