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WE‐B‐342‐01: Estimating Cancer Risk Attributable to Computed Tomography Coronary Angiography
Author(s) -
Einstein AJ
Publication year - 2008
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.2962681
Subject(s) - medicine , radiology , coronary angiography , breast cancer , lung cancer , coronary artery disease , ionizing radiation , radiation exposure , nuclear medicine , cancer , medical physics , myocardial infarction , irradiation , physics , nuclear physics
CT coronary angiography (CTCA) has become a popular diagnostic test for patients with known or suspected coronary artery disease. CTCA generates images of sub‐millimeter spatial resolution and has been validated in multicenter clinical trials to have high predictive value to exclude coronary disease. CTCA is now typically performed on a 64‐or‐greater slice multidetector‐row scanner in helical mode with low pitch. The resulting effective dose is on the order of 20 mSv, with breast and lung doses roughly 70 mGy. My colleagues and I have estimated potential cancer risks attributable to CTCA, using a combination of Monte Carlo methods to estimate organ doses of various protocols, and radioepidemiological modeling using the approach of the National Academies' Biological Effects of Ionizing Radiation (BEIR) VII report. In this lecture, I will address the clinical utilization of CTCA, methodology for estimating attributable cancer risks, cancer risk from CTCA, and the effects of patient age, gender, and scan protocol on risk. Educational Objectives: 1. Understand the information provided by CTCA, in comparison to other cardiac imaging modalities. 2. Know typical organ and effective doses from CTCA. 3. Learn how cancer risk attributable to CTCA depends on age and gender. 4. Understand approaches to lower radiation dose and cancer risk from CTCA.