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Dosimetric characterization of model Cs‐1 Rev2 cesium‐131 brachytherapy source in water phantoms and human tissues with MCNP5 Monte Carlo simulation
Author(s) -
Wang Jianhua,
Zhang Hualin
Publication year - 2008
Publication title -
medical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 180
eISSN - 2473-4209
pISSN - 0094-2405
DOI - 10.1118/1.2868754
Subject(s) - monte carlo method , brachytherapy , imaging phantom , dosimetry , anisotropy , dose rate , computational physics , physics , materials science , nuclear medicine , medical physics , medicine , optics , radiation therapy , mathematics , radiology , statistics
A recently developed alternative brachytherapy seed, Cs‐1 Rev2 cesium‐131, has begun to be used in clinical practice. The dosimetric characteristics of this source in various media, particularly in human tissues, have not been fully evaluated. The aim of this study was to calculate the dosimetric parameters for the Cs‐1 Rev2 cesium‐131 seed following the recommendations of the AAPM TG‐43U1 report [Rivard et al., Med. Phys. 31, 633–674 (2004)] for new sources in brachytherapy applications. Dose rate constants, radial dose functions, and anisotropy functions of the source in water, Virtual Water™, and relevant human soft tissues were calculated using MCNP5 Monte Carlo simulations following the TG‐43U1 formalism. The results yielded dose rate constants of 1.048, 1.024, 1.041, and 1.044 cGyh − 1U − 1in water, Virtual Water™, muscle, and prostate tissue, respectively. The conversion factor for this new source between water and Virtual Water™ was 1.02, between muscle and water was 1.006, and between prostate and water was 1.004. The authors’ calculation of anisotropy functions in a Virtual Water™ phantom agreed closely with Murphy's measurements [Murphy et al., Med. Phys. 31, 1529–1538 (2004)]. Our calculations of the radial dose function in water and Virtual Water™ have good agreement with those in previous experimental and Monte Carlo studies. The TG‐43U1 parameters for clinical applications in water, muscle, and prostate tissue are presented in this work.